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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRU
All Species:
25.45
Human Site:
S1038
Identified Species:
62.22
UniProt:
Q92729
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92729
NP_005695.3
1446
162423
S1038
A
L
E
R
R
G
Y
S
A
R
H
E
V
R
Q
Chimpanzee
Pan troglodytes
XP_513263
1483
166127
S1075
A
L
E
R
R
G
Y
S
A
R
H
E
V
R
Q
Rhesus Macaque
Macaca mulatta
XP_001115805
1350
152055
G959
F
T
A
W
P
E
H
G
V
P
Y
H
A
T
G
Dog
Lupus familis
XP_852271
1446
162532
S1038
A
L
E
R
R
G
Y
S
A
R
H
E
V
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
B1AUH1
1446
162475
S1038
A
L
E
R
R
G
Y
S
A
R
H
E
V
R
Q
Rat
Rattus norvegicus
Q64604
1898
211475
S1492
A
L
H
K
S
G
S
S
E
K
R
E
L
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6YI48
1434
161661
S1026
A
L
E
R
R
G
Y
S
A
R
H
E
V
K
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B3DK56
1444
162642
S1036
A
L
E
R
R
G
Y
S
A
K
H
E
V
C
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16621
2029
229038
N1623
Q
L
C
R
Q
G
F
N
D
R
R
E
I
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9BMN8
2200
246601
P1796
R
L
K
M
V
G
E
P
E
V
R
E
I
K
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
92.6
97
N.A.
95.3
25.6
N.A.
N.A.
84.9
N.A.
75.1
N.A.
24.5
N.A.
23.4
N.A.
Protein Similarity:
100
96.7
92.8
98.5
N.A.
97.3
41.6
N.A.
N.A.
92.5
N.A.
85.8
N.A.
41
N.A.
36.8
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
46.6
N.A.
N.A.
93.3
N.A.
86.6
N.A.
40
N.A.
20
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
66.6
N.A.
N.A.
100
N.A.
93.3
N.A.
73.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
10
0
0
0
0
0
60
0
0
0
10
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
60
0
0
10
10
0
20
0
0
90
0
0
0
% E
% Phe:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
90
0
10
0
0
0
0
0
0
10
% G
% His:
0
0
10
0
0
0
10
0
0
0
60
10
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% I
% Lys:
0
0
10
10
0
0
0
0
0
20
0
0
0
30
0
% K
% Leu:
0
90
0
0
0
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
10
0
10
0
0
0
0
0
% P
% Gln:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
80
% Q
% Arg:
10
0
0
70
60
0
0
0
0
60
30
0
0
50
0
% R
% Ser:
0
0
0
0
10
0
10
70
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
10
0
0
0
10
10
0
0
60
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
60
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _